SNEHA RANA
Welcome to My Site!
I invite you to take a moment and look around. To learn more about my background, experience, skills and how we could potentially work together, simply contact me.
BIO
I am an enthusiastic biologist working in the field of metabolomics and biomarker discovery. Currently, I am a Ph.D. scholar at the Indian Institute of Technology Bombay working under the supervision of Prof. Pramod Wangikar. My Ph.D. project involves performing untargeted metabolomics for biomarker discovery in Diabetes mellitus using LCMS and GCMS. The new biomarker/s discovered may help in the early diagnosis of the disease in the Indian population.
EDUCATION
2014-2016
M.SC ( BIOCHEMISTRY)
I have obtained masters from " The Maharaja SayajiRao University of Baroda", Vadodara, Gujarat"
2011-2014
B.SC (BIOTECHNOLOGY)
I have obtained a bachelors degree from Sardar Patel University, Vallabh Vidyanagar, Anand Gujarat
EXPERIENCE
Roles & Responsibilities
June 2017-November 2017
RESERCH AND DEVELOPMENT OFFICER, MERIL DIAGNOSTIC, VAPI
My work was to develop different ELISA kits. I had worked with developing Dengue NS1 ELISA kits. My role includes standardizing the ELISA method for Dengue NS1 detection- such as standardizing sample volume,
PROJECTS
PH.D. THESIS PROJECT
An Untargeted Metabolomics for novel biomarker discovery in Diabetes Mellitus
Diabetes mellitus is a chronic, gradually progressive metabolic disorder that later develops into life-threatening complications. Current biomarkers used for diabetes such as fasting blood sugar, glycated HBA1C, Oral glucose tolerance test are the diagnostic biomarkers and does not provide idea of prediabetic state which arises ~10 years ahead of the disease or about its future complications such Diabetes kidney disease and Diabetes cardiovascular disease. We aim to find new biomarkers that can predict Diabetes years before its onset and about its future complications such as diabetes-related chronic kidney disease and diabetes-related cardiovascular disease.
M.SC DISSERTATION PROJECT
Role of TNFA and ADIPOQ polymorphisms in Type 2 diabetes mellitus in Gujarat Population
The prevalence of diabetes is very high in the Gujarat region of India. The study aimed at assessing single nucleotide polymorphisms which may be responsible for making the population more prone to Diabetes. We identified that ADIPOQ +45 T/G is strongly linked with Type 2 diabetes mellitus in Gujarat population.
SKILLS
UNTARGETED METABOLOME PROFILING VIA LIQUID CHROMATOGRAPHY COUPLED MASS SPECTROMETRYÂ Â (LCMS) AND GAS CHROMATOGRAPHY COUPLED MS (GCMS
UNTARGETED METABOLOMICS DATA ANALYSIS SOFTWARE TOOLS- XCMS, MZ MINE 2.0, MS-DIAL, METABOKIT.
PCR BASED SNP DETECTION TECHNIQUES-Â RESTRICTION FRAGMENT LENGTH POLYMORPHISMS (RFLP) AND Â AMPLIFICATION REFRACTORY MUTATION SYSTEM (ARMS)
VOLUNTEER Teaching Assistance
October 2021-Ongoing
GUEST LECTURER
I teach undergrad students "Metabolomics" course at Department of Bioanalytical Sciences, Ramnarain Ruia Autonomous College, Mumbai-400019
30th July 2022- 17th Sept 200
TEACHING ASSISTANT for the NPTEL course" Introduction to Proteomics"
I used to take every Saturday problem-solving session for the course wherein I discussed the problems pertaining to the weekly content of the course as well as tried to address the students' queries and doubts.
November 2021-Ongoing
TEACHING ASSISTANTSHIP FOR CENTRAL FACILITY INSTRUMENT GC X GC MS AT IIT BOMBAY
My role involves instrument maintenance and sample analysis.
LET’S CONNECT
Biosystems Engineering Lab, Department of Chemical Engineering, Indian Institute of Technology,
Powai 400076, Mumbai,
Maharashtra
India
